Know these Ultram side effects

Ultram, which is the brand name for Tramadol is a prescription drug used in the treatment of moderate to severe pain conditions. It works similar to a narcotic drug, even though it is not a narcotic drug. Ultram is an opiate agonist and works as a pain reliever by altering the body's sensation to pain. Like any other medication, Ultram side effects are may occur while taking it.

Ultram side effects:

Ultram acts effectively in the treatment of pain. Along with its wanted effects, there are some possible side effects that may occur when taking Ultram, which includes

1. Gastrointestinal side effects:

Some of the most commonly experienced side effects include gastrointestinal upset such as nausea vomiting, dry mouth, abdominal bloating, indigestion or heartburn, constipation or diarrhoea. Patients who take this medication may experience a decrease in appetite.

2. Nervous system side effects:

Common nervous system side effects as a result of Ultram use include headache, dizziness, and somnolence. Other CNS side effects include hallucinations, emotional stability, euphoria (an unusual pleasant feeling), disorientation, mood swings, fainting, agitation, tremor, anxiety, and nervousness have also been reported in some patients. Rare side effects of Ultram include coordination disturbances, sleep disorders and confusion. Cases of delirium have been reported from elderly patients taking Ultram.

Ultram may cause severe drowsiness and so it is necessary that patients under this medication should take caution while driving or working on dangerous machinery. The effect of Ultram is increased with the use of other sleeping medications and alcohol use. Combination of these medications may cause a depressing effect on the central nervous system decreases breathing.

Signs of serotonin syndrome have also been reported in few cases with Ultram use. Serotonin syndrome symptoms include vomiting, diarrhoea, rapid heart rate, confusion or other mental charges, blood pressure changes, hallucinations, fever, overactive reflexes, sweating, shivering, agitation, shakiness, coma, seizures, and also or irregular breathing. These side effects are potentially serious and should be reported to the health care provider immediately.

3. Cardiovascular side effects:

Cardiovascular Ultram side effects are quite rare, which includes orthostatic hypotension, low blood pressure, high blood pressure, heart attacks, heart palpitations, weakened pulse, and tachycardia.

4. Allergic reaction:

Ultram is known to cause allergic reactions in individual who have a history of allergy to any opioid. Signs of allergic reactions include itching, hives, an unexplained rash, difficulty in breathing, wheezing, and swelling of the mouth or throat. Allergic reactions are potentially harmful and should be reported to the health care provider immediately.

5. Genitourinary side effects:

Genitourinary side effects caused by Ultram include difficulty in emptying the bladder completely, painful urination and frequent urination. It is a common side effect reported in less than 5% of the patients treated with Ultram.

6. Metabolic side effects:

Metabolic side effects are rare with Ultram use, and include hyponatremia reported in some patients.

7. Other side effects:

Other side effects caused by Ultram include menopausal symptoms, which are quite common and reported in 1 to 13 percent of the patient taking it. Other rare side effects of Ultram includes accidental injury, abnormal walking pattern, weight loss, changes in taste, concentration problems, depression, migraines, skin vesicle formation, speech problem, hearing problem, liver failure, ringing in the ears (tinnitus) and cataracts. These rare side effects occur in less than 5 percent of the population using Ultram. Since these side effects are uncommon, it is quite difficult to tell whether they are caused by the medication or something else. Any side effects that increases over time or become bothersome should be reported to the health care provider immediately.

8. Dependence:

Ultram is a centrally acting analgesic. So, it can cause physical dependence which is evidenced by the need for a higher dose to control the pain. Stopping the medication suddenly may create withdrawal symptoms such as insomnia, anxiety and agitation. To prevent the occurrence of withdrawal symptoms, it is advisable to take the medication as indicated by the physician. Physicians usually wean off the medication slowly for a period of time to avoid withdrawal symptoms from occurring.


Ultram, the centrally acting pain reliever works effectively to reduce moderate to severe pain conditions. Along with the required effects, possible Ultram side effects can also occur in individuals when taking it. To make Ultram use safe, it is important that patients should be aware of the possible side effects and take safety precautions promptly.





Supported Organizations: