Generic name- (Hydrocodone bitartrate and ibuprofen)
Vicoprofen is a prescribed medicine commonly known as painkiller. It contains a combination of two medicines- narcotic drug hydrocodone bitartrate and a pain relieving drug ibuprofen. Hydrocodone is an opioid pain medication classified under the group of drugs called narcotic pain relievers. Ibuprofen is categorized under Non-Steroidal Anti-inflammatory drugs (NSAIDS). Other inactive agents in vicoprofen include colloidal silicon dioxide, corn starch, croscarmellose sodium, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, and titanium dioxide.
Vicoprofen is used short term to relieve severe pain and inflammation. Both hydrocodone bitartrate and ibuprofen components help in treating pain in their own way. Hydrocodone has analgesic and antitussive properties similar to those of codeine. Though the precise action of hydrocodone is not known, it is believed to affect the opiate receptors in the brain. Ibuprofen possesses analgesic and anti-pyretic properties that help in inhibiting cyclooxygenase activity and prostaglandin synthesis.
- Vicoprofen is a habit-forming drug; hence should be used only when prescribed by your health care provider.
- Do not use this drug if you are allergic to non-steroidal anti-inflammatory drugs or opioids.
- Before using vicoprofen, talk to your doctor if you are having any of these existing medical conditions- heart diseases, blood pressure, history of heart surgery, heart attack or stroke, asthma or other breathing disorders, liver or kidney disease, history of brain tumor or head injury, stomach ulcer, history of stomach or intestinal bleeding, hypothyroid, urination problems, history of drug addiction or any mental disorder.
- Do not drink alcohol while you are on Vicoprofen as alcohol may increase the risk of stomach bleeding.
- While using this medicine, avoid driving or operating heavy machinery as the drug may impair your thinking or actions.
- Patients who have curvature of spine cannot take this medication.
- Take vicoprofen exactly as prescribed. Do not use it in larger doses or for longer periods than recommended by your doctor.
- Do not take it empty stomach. Take it with milk or food to avoid an upset stomach.
- Drink plenty of water while taking a course of vicoprofen so as to avoid constipation.
- Vicoprofen may cause constipation, hence increase your fibre intake while using this medication.
The recommended dose of Vicoprofen is one tablet- every four to six hours. Dosage should not exceed five tablets in a 24 hour period. The dose and frequency of the medicine is adjusted to suit individual requirements.
Some of the serious side effects associated with vicoprofen intake are- chest pain, shortness of breath, sudden numbness or weakness, headache, slurred speech, slow heartbeat, nausea, stomach pain, severe blistering and skin rash, fever, neck stiffness, seizure, purplish spots on the skin, swelling or rapid weight gain, easy bruising or bleeding and fainting/light-headedness. If you notice any of these symptoms, consult your physician immediately.
Some of the less severe side effects include dry mouth, blurred vision, mild nausea, constipation, indigestion, dizziness, vomiting and headache.
Some of the drugs that can potentially interact with this medicine include ant-depressants, aspirin and other NSAIDs, lithium, bronchodilators, atropine, methotrexate and bowel or bladder medications such as hyoscamine and Detrol. Talk to your physician if you are taking any of the above mentioned medications. If you are taking any over-the-counter medications or herbal supplements or alternative medicines, tell your doctor about all the non-prescribed and prescribed medications that you are taking.
Administration of this drug is not recommended during labor and delivery. The use of this medicine during pregnancy (especially late trimester) should be avoided.
Vicoprofen overdose can occur when the medicine is taken more than the recommended dose. Following an acute overdose, toxicity may result from any of the two active ingredients in vicoprofen- hydrocodone or ibuprofen. Serious overdose with hydrocodone is characterized by respiratory depression, Cheyne-Stokes respiration, increased sleepiness resulting in the stage of coma or stupor, flaccidity of skeletal muscle, low heart rate, hypotension and cold, clammy skin.
Serious overdose due to ibuprofen component in Vicoprofen include gastrointestinal irritation with bleeding or perforation, thrombocytopenia, kidney or liver damage, jaundice, meningitis, and aplastic anemia. Overdose with this medicine can be fatal; hence seek immediate medical help.